How about the touch screen jump or the screen position is misplaced?
You could move the photo frame to another location to check if there is any nearby current interference and reset the factory resetting.
What to do for the blank screen/pixel screen/flicker screen?
You could press the power button for 10s to restart the frame and unplug the adapter then plug it again.
Please follow the upgrading link to upgrade the frame.
https://www.amazon.com/clouddrive/share/6oHWdhHpdM89AqHMBHNDrwgCNvN6lTHIii7QnCM66qH
How to do with pixel Lines on the screen?
You could make a try for resetting the factory resetting.
How to deal with the issue for white etched horizontal lines on the screen serface?
You could keep the frame unplugging for days and try to wipe the screen with a soft towel.